Project: Sex and B chromosome enigmas

Project:

Sex and B chromosome enigmas: model systems for the study of chromosome and genome evolution 

Financial support: Thematic Project FAPESP 2015/16661-1

Principal Investigator (PI): Cesar Martins

Co-Principal Investigator (Co-PI): Adriane P Wasko

Co-Principal Investigator (Co-PI): Diogo C Cabral-de-Mello

 

Principal Investigator (PI): Cesar Martins

Co-Principal Investigator (Co-PI): Adriane P Wasko

Co-Principal Investigator (Co-PI): Diogo C Cabral-de-Mello

 

Host Institution: Institute of Biosciences of Botucatu, UNESP – São Paulo State University, Botucatu, SP, Brazil

 

Project action lines

Chromosomes are major components of cells, packing the genetic material in a perfect organized structural and functional pattern. However, the chromosomes behavior during cell cycle is subjected to genomic rearrangements producing a wide variety of functional consequences with impact in cell disorders and also generating evolutionary novelties. Although several factors that mediate genomic rearrangements are now known, there are still many unanswered questions. In the light of high throughput era in generation of biological data, chromosome studies have also advanced to a higher level exploring high scale analyses of DNA, RNA, and proteins, and their interactive networks. Therefore, this grant application intends to explore chromosomal polymorphism (associated to B chromosomes and sex chromosomes) as models to investigate the structural and functional nature of chromosomal rearrangements during evolution. In this way, the objective of this project is to analyze chromosome rearrangements in the light of massive molecular data obtained from different biological models, in order to advance in the identification of origin and fate of chromosome changes and to comprehend their evolutionary consequences. Additionally, the project also aims to perform the scientific divulgation of chromosome facts, in the light of an evolutionary and function perspective, in order to enforce a dialog between science and society.

 

Research Groups

Genomics and Cytogenomics of B Chromosomes
PI Cesar Martins – UNESP/Botucatu
Associate Researchers:
Danillo Pinhal – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP Brazil.
David A Ray – Texas Tech University, TX, USA
Guilherme Targino Valente – Agronomical Science Faculty, São Paulo State University (UNESP), Botucatu, SP Brazil.
Lucia Carbone – Oregon Health & Science University, Beaverton, OR, USA.
Lucilene Delazari dos Santos – CEVAP, UNESP – São Paulo State University, Botucatu, SP, Brazil.
Ney Lemke – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP Brazil.
Patrícia Pasquali Parise Maltempi – Institute of Bioscience, São Paulo State University (UNESP), Rio Claro, SP, Brazil.
Thomas David Kocher – University of Maryland, College Park, MD, USA.
Rachel O’Neill – University of Connecticut, Storrs, CT/USA.
Vladimir Pavan Margarido – Center of Biology Sciences and Health, UNIOESTE – West Paraná State University. Cascavel, PR, Brazil.
 
Students:
Adauto Lima Cardoso – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP Brazil.
Érica Ramos – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP Brazil.
Ivan Wolf – Agronomical Science Faculty, São Paulo State University (UNESP), Botucatu, SP Brazil.
Jordana Inácio Nascimento Oliveira – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP Brazil.
Lauana Fogaça de Almeida – Agronomical Science Faculty, São Paulo State University (UNESP), Botucatu, SP Brazil.
Leonardo Nazário de Moraes – Agronomical Science Faculty, São Paulo State University (UNESP), Botucatu, SP Brazil.
Luiz Henrique Cardoso – Agronomical Science Faculty, São Paulo State University (UNESP), Botucatu, SP Brazil.
Natália Bortholazzi Venturelli – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP Brazil.
Rafael Takahiro Nakajima – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP Brazil.
Rodrigo Oliveira – Agronomical Science Faculty, São Paulo State University (UNESP), Botucatu, SP Brazil.
Syed Farhan Ahmad – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP Brazil.
 
 Genomics and Cytogenenomics of Sex Chromosomes
Co-PI Diogo C Cabral-de-Mello – UNESP/Rio Claro, Brazil
Associate Researchers:
Frantisek Marec – Institute of Entomology, Biology Centre CAS, ?eské Bud?jovice, Czech Republic.
Marcelo Ricardo Vicari – UEPG – State University of Ponta Grossa, Ponta Grossa-PR, Brazil.
Maria Dulcetti Vibranovski – Department of Genetics and Evolutionary Biology, USP – University of São Paulo,São Paulo, SP, Brazil.
Michelle Orane Schemberger – UEPG – State University of Ponta Grossa, Ponta Grossa-PR, Brazil.
 
Students:
Amanda Piveta Schnepper – UEPG – State University of Ponta Grossa, Ponta Grossa-PR, Brazil.
Diogo Milani – Institute of Bioscience, São Paulo State University (UNESP), Rio Claro, SP, Brazil.
Octavio Manuel Palacios-Gimenez – Institute of Biosciences, São Paulo State University (UNESP), Rio Claro, SP, Brazil.
Viviane Demétrio do Nascimento – Federal University of Paraná, Curitiba, PR, Brazil.
 
Science Divulgation
Co-PI Adriane P Wasko – UNESP/Botucatu, Brazil
Associate Researchers:
Flavia Karina Delella – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP Brazil.
Ligia Souza Lima Silveira da Mota – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP, Brazil. 
Lorraine Mockford – Nova Scotia Community College – NSCC Online Learning, Halifax, Nova Scotia, Canada
Renato Eugênio da Silva Diniz – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP, Brazil.
Silvia Mitiko Nishida – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP, Brazil.
Stephen Wayne Mockford – Acadia University, Wolfville, Nova Scotia, Canada
Wagner Seixas da Silva – Leopoldo de Meis Biochemistry Institute, UFRJ – Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
 
Students:
Bianca Picado Gonçalves – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP Brazil.
Bruna Cristina Jeronimo – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP Brazil.
Cassiane Martins Barbosa – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP Brazil.
Marielly Campos – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP Brazil.
Talita Roberto Aleixo de Almeida – Institute of Biosciences, São Paulo State University (UNESP), Botucatu, SP Brazil.
http://www.ibb.unesp.br/#!/departamentos/morfologia/laboratorios/laboratorio-de-genomica-integrativa/projetos-em-andamento/bsex/
 

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